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News
- July 06 - This release of Secreted Protein Database is based on UniProt Knowledgebase Release 7.0, Reference Sequence Release 15.0 and Ensembl Release 39. This release contains 18256 entries. Now you can download them from Download page!
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Secreted protein means the protein which is secreted outside of cell membrane. Because they are presented within the extracellular space, they are often accessible to various drug delivery mechanisms. Based on a bioinformatic pipeline and manual check, we have developed a collection of secreted proteins from Human, Mouse and Rat proteomes, which includes sequences from SwissProt, Trembl, Ensembl and Refseq. Such a collection is named as SPD, Secreted Protein Database.
The 18152 entries were classified into fourteen
functional categories, including "apolipoprotein", "cytokine", "protease", "toxin", etc. To make the dataset more comprehensive, nine
related datasets were also collected, such as SPDI, Riken mouse
secretome, SwissProt vertebrate secreted proteins, SubLoc etc.
SPD web interface includes five modules:
- Browse: browse SPD proteins according to chromosomes and functional classification or GO assignments.
- Search: search protein of interest via protein ID, keywords, description or sequence.
- Download: download SPD sequences.
- Data statistics: how many data does SPD contain in each special division?
- Help: Frequently asked questions abort SPD, including SPD construction pipeline, introduction of protein entry display page, etc.
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